Phlebitis often occurs in conjunction with thrombosis and is then called thrombophlebitis or superficial thrombophlebitis. This often makes the surface of the tongue appear smooth. Atrophic glossitis as a clinical signs of severe anemia. Atrophic glossitis, also known as bald tongue, smooth tongue, hunter glossitis, moeller glossitis, or mollerhunter glossitis, is a condition characterized by a smooth glossy tongue that is often tenderpainful, caused by complete atrophy of the lingual papillae depapillation. Glossitis is a problem in which the tongue is swollen and inflamed. Glossitis definition of glossitis by the free dictionary. Glossitis is a condition where the tongue becomes inflamed and swollen.
The objective of this paper is to report a case of megaloblastic anemia in which oral. This later limits n5,10methylenethf formation by decreasing the synthesis of formylthf. It affects mainly the tongue, but can be present on the edges. Not only that, but her skin tone was also a peculiar grey color matching the color of her suit. Patients were free of neurologic symptoms and anemia at diagnosis.
Deliverted before the west dorset divisionon october 30th by j. Taste disorder involving hunters glossitis following. Atrophic glossitis, also known as bald tongue, 2 smooth tongue, hunter glossitis, moeller glossitis, or mollerhunter glossitis, 1 3 is a condition characterized by a smooth glossy tongue that is often tenderpainful, 1 4 caused by complete atrophy of. Mary is a 62 year old accountant who arrived in my office with a chief complaint of hair loss. The major function of this system is as a barrier against the external environment. Gilut glossitis free download as powerpoint presentation. Pdf atrophic glossitis burning agony of nutritional. Glossitis in vitamin b 12 deficiency is present in up to 25% of cases 2. Unlike deep vein thrombosis, the probability that superficial thrombophlebitis will cause a clot to break up and be transported in pieces to the lung is. We describe 4 patients with oral linear lesions associated with vitamin b12 deficiency. In this study, we evaluated whether there was an intimate association of the deficiency of hemoglobin, iron, vitamin.
Diseases of oral cavity is the property of its rightful owner. Many conditions affect the human integumentary systemthe organ system covering the entire surface of the body and composed of skin, hair, nails, and related muscle and glands. Therequireddaily zinc uptake of 8 to 10 mg per day is usually supplied through a normal diet, but deficiencies. Other causes include injury, irritation from tobacco or spicy foods, or a poor diet. Perrniciors anaemia is a very mysterious complaint, time namiie of whichl may perhaps. Some changes in tongue may be manifestations of systemic diseases, nutritional deficiencies and initial signs of severe illness e. Vitamin b 12 deficiency can present with several oral manifestations, which are considered nonspecific. There have been several additions and deletions in chapter 4 on tumours of the oral cavity and mobile tongue in the 2017 fourth edition of the world health organization classification of tumours of the head and neck.
Jul 20, 2016 the tongue is generally inflammed often described as beefy redin color. The tuberculum impar soon disappears posterior one third. Glossitis can make it hard for you to talk, chew, or swallow, especially if you get sores on your tongue. It also occurs in irondeficiency anaemia, in syphilis, erythema multiforme, pemphigus, behcets syndrome, lichen planus and may be caused by any persistent irritant, such as tobacco smoke, roughened teeth, badly fitting dentures or overuse of mouthwashes.
Glossitis is often a symptom of other conditions, such as. This list includes the main name for each condition, as well as alternate names. Common tongue conditions in primary care american family. Pernicious anemia also known as biermers disease is an autoimmune atrophic gastritis, predominantly of the fundus, and is responsible for a deficiency in vitamin b12 cobalamin due to its malabsorption. A range of factors, including allergies, anemia, and vitamin b12 deficiencies can lead to glossitis. We recommend the determination of vitamin b12 in such. Gi symptoms include loss of appetite, diarrhea, and hunters glossitis a swollen, beefy red, shiny tongue thats painful with a burning sensation. Browse the gard list of rare diseases and related terms to find topics of interest to you. Characteristically with the glossitis, glossodynia and glossopyrosis there is gradual atrophy of the papillae tongue that eventuates in a smooth or bald tongue hunters glossitis or moellers glossitis. Other symptoms may include shortness of breath, pale skin, chest pain, numbness in the hands and feet, poor balance, a smooth red tongue, poor reflexes, depression and confusion. Because of the neurological alterations in association with ataxic gait and low levels of vitamin b12, nuclear magnetic resonance of the cervical and thoracic spine was requested, which documented images compatible with subacute combined degeneration of the spine fig 2. Obesity is currently considered an epidemic that affects approximately 300 million people worldwide and is recognized as one of the major public health problems.
Inclusion on this list does not serve as official recognition by the nih that a disease is rare. Glositis comunes y su relacion con patologias organicas. The results of this case have important clinical implications for the diagnostic evaluation and management of patients with glossodynia and apparent bmd. A wide spectrum of drugs can sometimes give rise to numerous adverse orofacial manifestations, particularly dry mouth, taste disturbances, oral mucosal ulceration, andor gingival swelling. Her final diagnoses were atrophic glossitis and glossodynia secondary to vitamin b 12 deficiency, most likely due to pernicious anemia. The first description of vitamin b12 deficit was made by british physician thomas addison in 1855, who called it pernicious anemia and it was described as a disease that manifested itself with macrocytic anemia, glossitis, and neurological symptoms similar to the case presented 3. Taste disorder involving hunters glossitis following total. Hunters glossitis jaundice ldh and bilirubin elevation rare resistant and recurring mucocutaneous ulcers clinical features of b 12 deficiency1,5,6,10 neuropsychiatric classic combined sclerosis of the spinal cord frequent polyneurites especially sensitive ones ataxia babinskis phenomenon rare. The principal causes of b 12 deficiency include pernicious anemia, dietary deficiency, postsurgical malabsorption, and foodb 12 malabsorption. Vitamin b12 deficit and development of geriatric syndromes. Hunters glossitis, which presents in up to 25% of cases,2 is characterized by diffuse. Browse az genetic and rare diseases information center. State of art of oral vitamin b12 cobalamin treatment in. Atrophic glossitis is often linked to an underlying nutritional deficiency of iron, folic acid, vitamin b 12, riboflavin, or niacin and resolves with correction of the underlying condition.
An update on cobalamin deficiency in adults oup academic. Vitamin b 12 deficiency anemia, of which pernicious anemia is a type, is a disease in which not enough red blood cells are produced due to a deficiency of vitamin b 12. Abdominal ultrasonography, preferably with doppler sonography, is useful to detect appendicitis, especially in children. Some conditions that are not considered rare are on this list and are labeled. Find more information on glossitis, including symptoms, causes, types, and treatment. This chapter excludes the oropharynx, which now is a standalone chapter acknowledging the uniqueness of the oropharynx from the oral cavity.
The discovery of the disease was incidental in one patient who only had macrocytosis with no anemia 1. Familythe journal ofthe journal of practice 538 vol 56, no 7 july 2007 the journal of family practice spinal cord, hemolytic anemia and even pancytopenia table 1. The skin weighs an average of four kilograms, covers an area of two square metres, and is made of three distinct layers. Atrophic glossitis, also known as smooth tongue or atrophic papillae, always occurs when there is a loss of 50% of fungiform and filiform papillae on the dorsum of the tongue. Check the full list of possible causes and conditions now. Of note is the fact that there is typically a 5 to 10year delay between the onset of b 12 deficiency and the development of clinical illness, in part because of hepatic stores of cobalamin 1. A wide spectrum of drugs can sometimes give rise to numerous adverse orofacial manifestations, particularly dry mouth, taste disturbances, oral. Detect nutrient deficiencies with nfpe todays dietitian. Mar 30, 20 the first description of vitamin b12 deficit was made by british physician thomas addison in 1855, who called it pernicious anemia and it was described as a disease that manifested itself with macrocytic anemia, glossitis, and neurological symptoms similar to the case presented 3. Glossitis definition of glossitis by medical dictionary. Atrophic glossitis ag is considered to be a marker of nutritional deficiency. Ppt diseases of oral cavity powerpoint presentation. The tongue is generally inflammed often described as beefy redin color. The tongue looks smooth and may be an unusual colour from pinkish to dark red.
Zinc zinc is an essential cofactor of several metaloenzymesandtranscriptionfactors. Gilut glossitis cutaneous conditions health sciences. Phlebitis or venitis is the inflammation of a vein, usually in the legs. Started in 1995, this collection now contains 6767 interlinked topic pages divided into a tree of 31 specialty books and 732 chapters. Hunters glossitis or moellerhunter is the most classic form. If so, share your ppt presentation slides online with. Allergic reactions to oral care products, foods, or medicine. Ultrasound can show the free fluid collection in the right iliac fossa, along with a visible appendix with increased blood flow when using color doppler, and noncompressibility of the appendix, as it is essentially walledoff abscess. Sep 25, 2017 glossitis is an inflammation of the tongue. The classic oral manifestations of vitamin b12 deficiency are considered nonspecific. Thus, homocysteine accumulates, methionine and in term sadenosylmethionine decrease.
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